Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections.

During HIV pathogenesis, infected macrophages behave as "viral reservoirs" that accumulate and retain virions within dedicated internal Virus-Containing Compartments (VCCs).The nature of VCCs remains ill characterized and controversial.Using wild-type HIV-1 and a replication-competent HIV-1 carrying GFP internal to the Gag precursor, we analyzed th

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A new species of Stenasellus Dollfus, 1897 from Iran, with a key to the western Asian species (Crustacea, Isopoda, Stenasellidae)

A new stenasellid isopod is described from Tashan Cave, Khuzestan Province, south-west Iran, Suspension Shock Absorber Bracket belonging to the genus Stenasellus Dollfus, 1897.The first recorded species of Stenasellidae from Iran, Stenasellus tashanicus sp.n., is diagnosed by the presence of antennae with a minute squama bearing paired, long, robus

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Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma

29-year-old Hispanic woman presented to the clinic with complaints of abdominal pain, nausea, fatigue, and constipation.Laboratory tests indicated the presence of iron deficiency anemia and transaminitis.Imaging evaluation revealed marked hepatomegaly with multiple hepatic metastases and pelvic lymphadenopathy.Biopsy of the hepatic lesions showed a

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